LS1 (9-11) FAF+ POC -2 Explain or justify with evidence how the alteration of the DNA sequence may produce new gene combinations that make little difference, enhance capabilities, or can be harmful to the organism (e.g., selective breeding, genetic engineering, mutations).

LS1(9-11)–2 Students demonstrate an understanding of the molecular basis for heredity by
2a describing the DNA structure and relating the DNA sequence to the genetic code.
2b explaining how DNA may be altered and how this affects genes/heredity (e.g. substitution, insertion, or deletion).
2c describing how DNA contains the code for the production of specific proteins.

Example Extension(s) LS1 (Ext) –2 Students demonstrate an understanding of the molecular basis for heredity by …
2aa diagramming or modeling the relationship between chromosomes, genes and DNA, including histones and nucleosomes.
2bb describing the how foods are genetically modified and the potential health, environmental and economic advantages and disadvantages of doing so.
2cc tracing in a diagram or model the information flow - DNA to RNA to Protein –through transcription and translation.

Example Extension(s) LS3 (Ext) -6 Students will demonstrate their understanding of the degree of genetic relationships among organisms by …
6aa describing how the Human Genome Project has contributed to our understanding of both human heredity and the commonality of DNA sequences among organisms.